Thermo Fisher Scientific IL17RC Recombinant Rabbit Monoclonal Antibody (209)
Human IL17RC 특이적 재조합 토끼 단클론 항체로, 높은 특이성과 민감도를 제공하며 로트 간 일관성이 우수합니다. ELISA에 적합하며 보존제가 없는 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관을 권장합니다.
- 카탈로그번호
- MA530540
- 판매단위
- pk
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Applications
- ELISA
Tested Dilution
- 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 209 |
| Immunogen | Recombinant Human IL17RC protein (Met1–Ala454) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786259 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
This antibody has specificity for Human IL17RC.
Target Information
The IL17RC gene encodes a single-pass type I membrane protein similar to the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is mainly expressed in hemopoietic cells and binds only IL-17A, IL17RC is expressed in nonhemopoietic tissues and binds both IL-17A and IL-17F with similar affinities.
IL-17A and IL-17F are proinflammatory cytokines implicated in inflammatory and autoimmune disease progression. Multiple alternatively spliced transcript variants encoding different isoforms have been detected, and soluble secreted forms may act as extracellular antagonists to cytokine signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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