Thermo Fisher Scientific IL17RB Monoclonal Antibody (09)
Human IL17RB 단백질을 인식하는 Mouse monoclonal antibody로, ELISA에 적합하며 preservative-free 포뮬레이션. 단백질 A로 정제되었고 1 mg/mL 농도로 제공. 장기 보관 시 -20°C에서 보관 권장.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 09 |
| Immunogen | Recombinant Human IL17BR/IL17RB/IL-17 Receptor B Protein (Met1–Gly289) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786258 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human IL17BR / IL17RB / IL-17 Receptor B.
Target Information
A number of cytokines belonging to the interleukin (IL)-17 family have been identified, including IL-17B, IL-17C, and IL-17E.
IL-17 is a potent proinflammatory cytokine involved in diseases such as rheumatoid arthritis, multiple sclerosis, and tumor growth promotion.
IL-17B, C, and E can induce proinflammatory responses but do not bind to the IL-17 receptor, suggesting additional IL-17R-related receptors exist.
Receptors for IL-17B and IL-17E have been identified as EV127 (mouse) and IL-17Rh1 (human).
IL-17E activates the NF-kB pathway and induces IL-8 production. IL-17Rh1 mRNA is highly expressed in kidney and liver, with moderate expression in small intestine, colon, and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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