
Thermo Fisher Scientific Neurofilament (NF-L) (Neuronal Marker) Monoclonal Antibody (NFL/736)
신경세포 마커 NF-L을 인식하는 단클론 항체로, 면역조직화학, 면역세포화학, 유세포분석 등 다양한 응용에 사용 가능. 인간, 설치류, 조류 등 다양한 종에 반응하며, 단백질 A/G로 정제된 고품질 항체. 냉동 보관(-20°C) 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.25–0.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 2–4 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Bovine, Chicken, Human, Pig, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | NFL/736 |
| Immunogen | Recombinant human NEFL protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Neurofilaments are intermediate filament proteins found specifically in neurons and are essential for maintaining neuronal caliber. They consist mainly of three subunits: NF-L (light), NF-M (medium), and NF-H (heavy).
- NF-L (Neurofilament Light): Low molecular weight subunit (~70 kDa)
- NF-M (Neurofilament Medium): Intermediate molecular weight
- NF-H (Neurofilament Heavy): High molecular weight subunit (180–220 kDa, species-dependent)
The expression of these neuronal intermediate filament proteins is both tissue-specific and developmentally regulated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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