Thermo Fisher Scientific CD70 Monoclonal Antibody (OTI13D7)

Applications

• Flow Cytometry (Flow)
  Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) to ensure carrier-free conditions.

Target Information

The CD70 protein is a cytokine belonging to the tumor necrosis factor (TNF) ligand family and acts as a ligand for TNFRSF27/CD27. It is expressed on activated T and B lymphocytes but not on resting cells. CD70 promotes T cell proliferation, enhances cytolytic T cell generation, and supports T cell activation. It also plays roles in regulating B-cell activation, NK cell cytotoxicity, and immunoglobulin synthesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.