Thermo Fisher Scientific CD70 Monoclonal Antibody (OTI5E9)
인간 CD70 단백질을 인식하는 Mouse IgG1 단클론 항체로, Flow Cytometry에 적합합니다. 동결건조 형태로 제공되며, PBS와 8% 트레할로스 용액에 재구성 가능합니다. 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용됩니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E9 |
| Immunogen | Full length human recombinant protein of human CD70 (NP_001243) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The CD70 protein is a cytokine belonging to the tumor necrosis factor (TNF) ligand family and acts as a ligand for TNFRSF27/CD27. It is expressed on activated T and B lymphocytes but not on resting cells. CD70 promotes proliferation of costimulated T cells, enhances cytolytic T cell generation, and contributes to T cell activation. It also plays roles in regulating B-cell activation, NK cell cytotoxicity, and immunoglobulin synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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