Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI10F9), TrueMAB
KLK8 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC/IF 등에 사용 가능. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용. 인간 KLK8 단백질 전체 길이를 면역원으로 제작됨. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10F9 |
| Immunogen | Full length human recombinant protein of human KLK8 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological roles. Many kallikreins are implicated in carcinogenesis and may serve as biomarkers for cancer and other diseases.
The KLK8 gene is part of a kallikrein gene cluster on chromosome 19 and may be involved in proteolytic cascades in the skin, serving as a potential biomarker for ovarian cancer.
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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