Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI6F4), TrueMAB
인간 KLK8 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 ICC/IF에 사용 가능. 동결건조 형태로 제공되며, 재구성 시 약 1 mg/mL 농도 권장. 암 및 질병 바이오마커 연구에 적합. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6F4 |
| Immunogen | Full length human recombinant protein of human KLK8 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological roles. Many kallikreins are implicated in carcinogenesis and have potential as biomarkers for cancer and other diseases.
The KLK8 gene is one of fifteen kallikrein subfamily members located in tandem on chromosome 19. The encoded protein may participate in proteolytic cascades in the skin and serve as a biomarker for ovarian cancer.
Alternate splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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