Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI5B4), TrueMAB
인간 KLK8 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, IHC, ICC/IF에 사용 가능. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. 암 연구 및 바이오마커 탐색에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B4 |
| Immunogen | Full length human recombinant protein of human KLK8 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological functions. Many kallikreins are implicated in carcinogenesis and may serve as novel biomarkers for cancer and other diseases.
KLK8 is one of fifteen kallikrein subfamily members located in tandem on chromosome 19. The encoded protein may participate in proteolytic cascades in the skin and serve as a biomarker for ovarian cancer.
Alternate splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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