Thermo Fisher Scientific MEK1/MEK2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human MAP2K1 (NP_0027461) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MEK1/2,uniProtId:Q02750-1,ncbiNodeId:9606,antigenRange:200-300,antigenLength:393,antigenImageFileName:PA5-116802_MEK12_Q02750-1_Rabbit.svg,antigenImageFileNamePDP:PA5-116802_MEK12_Q02750-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.12 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901433

Product Specific Information

Positive Samples: PC-12, U-87MG, Mouse brain, Rat brain

Immunogen sequence: SRGEIKLCDF GVSGQLIDSM ANSFVGTRSY MSPERLQGTH YSVQSDIWSM GLSLVEMAVG RYPIPPPDAK ELELMFGCQV EGDAAETPPR PRTPGRPLSS Y

Target Information

MEK 1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003). In brain, this pathway also plays a key role in synaptic (Adams and Sweatt, 2002). Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.