Thermo Fisher Scientific MEK1/MEK2 Polyclonal Antibody
Thermo Fisher Scientific의 MEK1/MEK2 Polyclonal Antibody는 Human, Mouse, Rat 시료에 반응하며 Western Blot 및 ELISA에 적합합니다. Rabbit IgG 기반의 비결합 항체로, 액상 형태이며 -20°C에서 보관합니다. MAP2K1 항원 서열(200–300 aa)을 인식합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 200–300 of human MAP2K1 (NP_002746.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.12 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901433 |
Product Specific Information
- Positive Samples: PC-12, U-87MG, Mouse brain, Rat brain
- Immunogen Sequence:
SRGEIKLCDF GVSGQLIDSM ANSFVGTRSY MSPERLQGTH YSVQSDIWSM GLSLVEMAVG RYPIPPPDAK ELELMFGCQV EGDAAETPPR PRTPGRPLSS Y
Target Information
MEK1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003). In the brain, this pathway also plays a key role in synaptic regulation (Adams and Sweatt, 2002). Activated MEK1 acts as a dual specificity kinase phosphorylating both threonine and tyrosine residues on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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