Thermo Fisher Scientific HSPB11 Polyclonal Antibody
Thermo Fisher Scientific의 HSPB11 Polyclonal Antibody는 Human, Mouse, Rat에서 반응하며 Western blot, IHC, ICC/IF, ELISA에 적합합니다. Rabbit IgG 기반 액상 항체로, 0.9 mg/mL 농도로 제공되며 PBS buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific HSPB11 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 1–144 of human HSPB11 (NP_0572102) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.90 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901439 |
Product Specific Information
- Positive Samples: A-549, 293T, Mouse kidney, Mouse brain, Rat thymus
- Immunogen Sequence:
MRKIDLCLSS EGSEVILATS SDEKHPPENI IDGNPETFWT TTGMFPQEFI ICFHKHVRIE RLVIQSYFVQ TLKIEKSTSK EPVDFEQWIE KDLVHTEGQL QNEEIVAHDG SATYLRFIIV SAFDHFASVH SVSAEGTVVS NLSS
Target Information
HSPB11 (Heat shock protein beta-11), also known as IFT25, was originally identified as a small heat shock protein. Recently, it has been identified as a component of IFT complex B. IFT25 is not required for ciliary assembly but is essential for proper Hedgehog signaling, which occurs within cilia in mammals. Cilia lacking IFT25 show defects in signal-dependent transport of Hedgehog components and fail to activate the pathway upon stimulation.
Safety and Usage Notes
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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