Thermo Fisher Scientific FXN Monoclonal Antibody (18A5DB1)

Applications

Tested Dilution

Publications

Western Blot (WB)

3-5 µg/mL

View 2 publications 2 publications

Immunohistochemistry (IHC)

10 µg/mL

-

Immunocytochemistry (ICC/IF)

0.5 µg/mL

-

Flow Cytometry (Flow)

1 µg/mL

-

ChIP assay (ChIP)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

18A5DB1

Immunogen

Human frataxin (full length mature form, residues 56-210) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FXN,uniProtId:Q16595-1,ncbiNodeId:9606,antigenRange:56-210,antigenLength:210,antigenImageFileName:45-6300_FXN_Q16595-1_House_mouse.svg,antigenImageFileNamePDP:45-6300_FXN_Q16595-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

IgG fraction

Storage buffer

HEPES buffered saline

Contains

0.02% sodium azide

Storage conditions

4° C, do not freeze

Shipping conditions

Wet ice

RRID

AB_2533823

Product Specific Information

Positive controls: Recombinant Human Frataxin; normal Human fibroblasts (MRC5); HL60 cells. This antibody gave a positive result in IHC in the following FFPE tissue: Human colon adenocarcinoma.

Target Information

FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.