Thermo Fisher Scientific Mitofilin Monoclonal Antibody (2E4AD5)
Mitofilin 단백질을 검출하기 위한 Thermo Fisher Scientific의 Mouse Monoclonal Antibody. Western Blot, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합. 고순도 정제된 액상 형태로 1 mg/mL 농도 제공. 인체 및 다양한 종의 미토콘드리아 연구용으로 최적화.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | 1–5 µg/mL | - |
| Flow Cytometry (Flow) | 1 µg/mL | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2E4AD5 |
| Immunogen | Human heart mitochondria (Target Family: Mitofilin, UniProt ID: Q16891-1, Antigen Range: 1–758, Antigen Length: 758) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | HEPES buffered saline |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_2533824 |
Product Specific Information
Positive controls: Human fibroblasts, Human cerebellum tissue, Isolated mitochondria from Human, Bovine, Rat and Mouse hearts, HepG2 lysate, HL60 cells.
This clone can also be referred to as clone number MM#7A-2E4AD5.
Target Information
Mitofilin is a transmembrane protein located in the inner mitochondrial membrane. It is associated with a large multimeric protein complex (~1200 kDa) and plays a critical role in mitochondrial morphology, fusion, and fission—particularly in the formation of tubular cristae and cristae junctions.
Abnormal mitochondrial morphology has been implicated in various human diseases such as myopathy, cardiomyopathy, rhabdomyosarcoma, and Whartin’s tumor.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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