Thermo Fisher Scientific Cyclophilin F Monoclonal Antibody (E11AE12BD4)
Cyclophilin F 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot, IHC, ICC, Flow cytometry, IP 등 다양한 응용에 적합합니다. 인간, 소, 생쥐, 랫드 반응성을 가지며, 고순도 정제 및 안정적 액상 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1.0 µg/mL | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | - |
| Flow Cytometry (Flow) | 1 µg/mL | - |
| Immunoprecipitation (IP) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E11AE12BD4 |
| Immunogen | Recombinant rat Cyclophilin F |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | HEPES buffered saline |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_2533820 |
Product Specific Information
Positive controls include isolated mitochondria from human, bovine, rat, and mouse heart tissues; HepG2 cells; cultured human embryonic lung-derived fibroblasts (strain MRC5); human cerebellum tissue; and HL60 cells.
Target Information
The Cyclophilin F protein belongs to the peptidyl-prolyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides, facilitating protein folding. Cyclophilin F is a component of the mitochondrial permeability transition pore located in the inner mitochondrial membrane. Activation of this pore is implicated in apoptotic and necrotic cell death mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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