Thermo Fisher Scientific BRG1 Monoclonal Antibody (A5C9)
BRG1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. 인간 시료에 반응하며 Western blot 및 IHC(P) 응용에 적합. 핵 내 BRG1 단백질 검출에 유용하고, 고순도 Protein G 정제 및 안정적 액상 형태로 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A5C9 |
| Immunogen | Synthetic peptide within human BRG1 aa 230–280/1647 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | TBS, pH 7.4, with 0.1% BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091237 |
Product Specific Information
- Positive Control: K562 cell lysate, 293T cell lysate, human kidney tissue
- Predicted Band Size: 185 kDa
- Subcellular Location: Nucleus
Target Information
Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair, and DNA replication.
Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes, including those involved in interferon and stress response, immune cell differentiation, neurogenesis, and cell cycle regulation.
Brg1 is absolutely necessary for mouse embryogenesis and is also involved in cell growth arrest, senescence, and tumor suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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