Thermo Fisher Scientific PRL1 Polyclonal Antibody
PRL1 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody. Western blot에 적합하며 인간 시료에 반응. C-말단 합성 펩타이드 면역원 사용. 고순도 액상 형태로 -20°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- PA517986
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KDSNGHRNNCCIQ) corresponding to the C-terminus amino acids of PTP4A1 (aa 161–173) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980815 |
Product Specific Information
- This antibody is predicted to react with canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:2000.
Target Information
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), containing a PTP domain and a characteristic C-terminal prenylation motif.
PTPs are cell signaling molecules that regulate various cellular processes.
This tyrosine phosphatase is a nuclear protein but may associate with the plasma membrane depending on its C-terminal prenylation.
Overexpression in mammalian cells confers a transformed phenotype, suggesting a role in tumorigenesis.
In rat studies, this gene may act as an immediate-early gene in mitogen-stimulated cells.
PRL phosphatases increase cell proliferation by stimulating progression from G1 to S phase.
PRL-1 function is cell cycle-dependent and may regulate mitosis by modulating spindle dynamics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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