Thermo Fisher Scientific ATF4 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.3–1 µg/mL

Product Specifications

Product Specific Information

• Predicted to react with porcine and rat based on sequence homology.
• Tested in Peptide ELISA: antibody detection limit dilution 128,000.

Target Information

This gene encodes a transcription factor originally identified as a mammalian DNA-binding protein that binds a tax-responsive enhancer element in the LTR of HTLV-1.
It was also characterized as cAMP-response element binding protein 2 (CREB-2).
The encoded protein belongs to a family of DNA-binding proteins including AP-1, CREBs, and CREB-like proteins.
These transcription factors share a leucine zipper region for protein-protein interactions, located C-terminal to a basic amino acid stretch functioning as a DNA binding domain.
Two alternative transcripts encoding the same protein have been described.
Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.