Thermo Fisher Scientific DUSP16 Polyclonal Antibody
Goat 유래 DUSP16 폴리클로날 항체로, Human에 반응하며 IHC(P)에서 2-4 µg/mL 농도로 사용 가능. MAPK 단백질 탈인산화 연구에 적합하며, 고순도(암모늄 황산 침전)로 정제된 액상 형태. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–4 µg/mL
- Publications: [References not available]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (AHEMIGTQIVTER) corresponding to the N-terminus amino acids of DUSP16 (aa 2–15) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10999957 |
Product Specific Information
- Predicted to react with bovine, canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
- Preliminary analysis showed no signal in Western Blot.
Target Information
Dual-specificity phosphatases (DUSPs) are a heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily.
DUSPs can dephosphorylate both tyrosine and serine/threonine residues.
DUSP16, also known as MKP-7, dephosphorylates MAPK proteins ERK, JNK, and p38 with distinct specificity.
MKPs contain a conserved C-terminal catalytic domain and an N-terminal Cdc25-like domain.
MAPK activation cascades mediate various physiological processes such as cellular proliferation, apoptosis, differentiation, and stress responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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