Thermo Fisher Scientific Kappa Light Chain Recombinant Rabbit Monoclonal Antibody (IGKC, 1999R)
Recombinant rabbit monoclonal antibody targeting human kappa light chain (IGKC). Suitable for IHC and peptide array applications. High purity, unconjugated form, optimized for research use. Supplied as liquid, 1 mg/mL in PBS without preservative.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | IGKC, 1999R |
| Immunogen | Recombinant full-length human Ig kappa light chain (IGKC) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For immunohistochemistry on PFA-fixed tissues, incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Immunoglobulin classes share a basic structure of four polypeptide chains: two heavy chains and two light chains (kappa and lambda, each ~22.5 kDa).
Kappa and lambda light chains consist of a variable and constant region and can be differentiated by their antigenic properties.
The typical ratio of kappa to lambda is 70:30.
Antibodies to the kappa light chain are useful for identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
Demonstration of clonality in lymphoid infiltrates indicates malignancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 항원 관련 이미지 파일명: 3514-RBM9-P1ABX_Kappa_Light_Chain_P01834-1_Rabbit.svg, 3514-RBM9-P1ABX_Kappa_Light_Chain_P01834-1_Rabbit_PDP.jpeg)
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