
Thermo Fisher Scientific Phospho-Vasopressin Receptor 2 (Ser362, Ser363, Ser364) Polyclonal Antibody
인간 AVPR2 인산화 부위(Ser362/Ser363/Ser364)에 특이적인 폴리클로날 항체입니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human V2 around the phosphorylation site of Ser362/Ser363/Ser364 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Avpr2 is a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone synthesized in the supraoptic and paraventricular nuclei of the hypothalamus. It is transported to the neurohypophysis in neurosecretory vesicles, where it is stored or secreted into the bloodstream.
Avpr2 acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has antidiuretic effects on the kidney, induces vasoconstriction, and can contract smooth muscle during parturition and lactation. Avpr2 is also involved in cognition, tolerance, adaptation, sexual and maternal behavior, and regulation of water excretion and cardiovascular functions. Its activity is mediated by G proteins that activate adenylate cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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