Thermo Fisher Scientific Phospho-Vasopressin Receptor 2 (Ser350) Polyclonal Antibody
인간 V2 수용체 Ser350 인산화 부위를 인식하는 토끼 다클론 항체로, Western blot에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태. 단기 4°C, 장기 -20°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- 7TM0368A
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human V2 around the phosphorylation site of Ser350 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Avpr2 is a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone synthesized in the supraoptic and paraventricular nuclei of the hypothalamus. Together with its carrier protein neurophysin 2, it is packaged into neurosecretory vesicles and transported to the neurohypophysis for storage or secretion.
Avpr2 acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and induces vasoconstriction of peripheral vessels. Additionally, Avpr2 participates in smooth muscle contraction during parturition and lactation, cognition, tolerance, adaptation, and complex sexual and maternal behavior, as well as regulation of water excretion and cardiovascular functions. Its activity is mediated by G proteins activating adenylate cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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