Thermo Fisher Scientific Phospho-Vasopressin Receptor 2 (Ser350) Polyclonal Antibody

Applications

• Western Blot (WB): Tested dilution 1:1,000

Product Specifications

Target Information

Avpr2 is a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone synthesized in the supraoptic and paraventricular nuclei of the hypothalamus. Together with its carrier protein neurophysin 2, it is packaged into neurosecretory vesicles and transported to the neurohypophysis for storage or secretion.

Avpr2 acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and induces vasoconstriction of peripheral vessels. Additionally, Avpr2 participates in smooth muscle contraction during parturition and lactation, cognition, tolerance, adaptation, and complex sexual and maternal behavior, as well as regulation of water excretion and cardiovascular functions. Its activity is mediated by G proteins activating adenylate cyclase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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