Thermo Fisher Scientific Phospho-Oxytocin Receptor (Ser377, Ser378) Polyclonal Antibody
인간 Oxytocin 수용체의 Ser377/Ser378 인산화 부위를 인식하는 rabbit polyclonal antibody입니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 7TM0369B
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human oxytocin receptor around the phosphorylation site of Ser377/Ser378 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The oxytocin receptor (OXTR) belongs to the G-protein coupled receptor family. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The receptor consists of 389 amino acids with a molecular weight of approximately 43 kDa.
The oxytocin-oxytocin receptor system plays a critical role in uterine contraction during parturition and milk ejection. Oxytocin receptors are expressed in the mammary gland myoepithelial cells, and in both the myometrium and endometrium of the uterus at the end of pregnancy. Additionally, oxytocin receptors are present in the central nervous system, mediating various behaviors such as maternal bonding, social recognition, sexual and aggressive behaviors, and responses to stress and anxiety.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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