Thermo Fisher Scientific KISS1R Polyclonal Antibody
Human KISS1R 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 3–5 µg/mL 농도로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 용액에 0.1% sodium azide를 포함. 내분비 기능 조절 및 사춘기 발현 관련 연구에 적합.
- 카탈로그번호
- PA533879
- 판매단위
- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 3–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from C-terminus of human KISS1R / GPR54 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551248 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gibbon, Monkey (95%)
- Marmoset (80%)
Target Information
GCPR54 (also known as KISS1R) is a galanin-like G protein coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1.
The tissue distribution of this protein suggests a role in the regulation of endocrine function and the onset of puberty.
GPR54 is expressed in various human brain regions, placenta, pancreas, and spinal cord, and at lower levels in spleen, peripheral blood leukocytes, testis, lymph node, thymus, small intestine, stomach, lung, and kidney. It is also abundant in tumor tissues.
In rat, GPR54 is expressed in liver, intestine, and multiple brain regions including pons, midbrain, thalamus, hypothalamus, hippocampus, amygdala, cortex, and striatum.
ESTs have been isolated from normal placenta and kidney cancer libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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