Thermo Fisher Scientific KISS1R Polyclonal Antibody
KISS1R 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 2.5–20 µg/mL 농도로 사용 가능. 인간, 돼지, 소, 염소 등에서 반응하며, 항원 친화 크로마토그래피로 정제됨. 내분비 기능 및 사춘기 발현 연구에 적합.
- 카탈로그번호
- PA533878
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2.5–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Pig, Bovine, Goat, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human KISS1R / GPR54 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551247 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Bovine, Goat, Pig (100%)
Monkey, Mouse, Bat, Dog (94%)
Gibbon, Marmoset, Rat, Hamster (89%)
Target Information
GCPR54 is a galanin-like G protein coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the protein suggests involvement in endocrine regulation and the onset of puberty.
GPR54 expression has been reported in various human brain regions, placenta, pancreas, and spinal cord, with lower levels in spleen, blood leukocytes, testis, lymph node, thymus, small intestine, stomach, lung, and kidney. The receptor is also abundant in tumor tissues.
In rat, GPR54 is expressed in liver, intestine, and several brain regions including pons, midbrain, thalamus, hypothalamus, hippocampus, amygdala, cortex (including frontal), and striatum. ESTs have been isolated from normal placenta and kidney cancer libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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