Thermo Fisher Scientific CD6 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
• Predicted reactivity: Human (99%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL).
CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse.
CD6-ALCAM mediated cell adhesion is also important for T cell proliferation.
CD6 may exert some of its functions via association with CD5, probably by fine-tuning CD5 signaling.
Ligation of CD6 has an antiapoptotic role in chronic lymphocytic leukemia B cells.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

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