Thermo Fisher Scientific CD6 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CD6 protein for Western blot applications. High specificity and predicted 99% reactivity with human samples. Supplied as a liquid unconjugated form, ideal for T cell activation studies. Store at 4°C short term...
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- PA529900
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 449–622 of Human CD6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.58 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547374 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
- Predicted reactivity: Human (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL).
CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse.
CD6-ALCAM mediated cell adhesion is also important for T cell proliferation.
CD6 may exert some of its functions via association with CD5, probably by fine-tuning CD5 signaling.
Ligation of CD6 has an antiapoptotic role in chronic lymphocytic leukemia B cells.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-29900_CD6_P30203-1_Rabbit.svg / PA5-29900_CD6_P30203-1_Rabbit_PDP.jpeg)
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