Thermo Fisher Scientific DAXX Polyclonal Antibody
인간 DAXX 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot, IHC, ICC/IF에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 인간 반응성, 비결합형 액상 형태로 제공되며 연구용으로 사용됩니다.
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Thermo Fisher Scientific DAXX Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 8–317 of Human DAXX |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.63 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547068 |
Product Specific Information
- Recommended positive controls: A431, H1299, HeLa, HepG2, Molt-4, Raji
- Predicted reactivity: Mouse (86%), Rat (88%), Bovine (93%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and cytoplasm. It interacts with various proteins such as apoptosis antigen Fas, centromere protein C, and transcription factor E26 oncogene homolog 1.
In the nucleus, it functions as a transcription repressor binding to sumoylated transcription factors, with repression relieved by sequestration into promyelocytic leukemia nuclear bodies or nucleoli.
It also associates with centromeres in G2 phase and may regulate apoptosis in the cytoplasm.
Subcellular localization and function are modulated by post-translational modifications including sumoylation, phosphorylation, and polyubiquitination.
Alternative splicing results in multiple transcript variants.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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