Thermo Fisher Scientific BMP-7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 70-251 of BMP7 (NP_0017101) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BMP-7,uniProtId:P18075-1,ncbiNodeId:9606,antigenRange:70-251,antigenLength:431,antigenImageFileName:PA5-87488_BMP-7_P18075-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87488_BMP-7_P18075-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.65 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804193

Product Specific Information

Immunogen sequence: PHLQGKHNSA PMFMLDLYNA MAVEEGGGPG GQGFSYPYKA VFSTQGPPLA SLQDSHFLTD ADMVMSFVNL VEHDKEFFHP RYHHREFRFD LSKIPEGEAV TAAEFRIYKD YIRERFDNET FRISVYQVLQ EHLGRESDLF LLDSRTLWAS EEGWLVFDIT ATSNHWVVNP RHNLGLQLSV ET

Positive Samples: MCF-7, Mouse kidney

Target Information

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.