Thermo Fisher Scientific CDK6 Polyclonal Antibody
CDK6 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(Paraffin) 실험에 사용 가능. 세포주 및 조직에서 CDK6 발현 분석에 적합. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids 250–326 of human CDK6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.96 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804195 |
Product Specific Information
- Positive Samples: Jurkat, Mouse liver, Rat brain
- Cellular Location: Cell projection, Cytoplasm, Nucleus, Centrosome, Cytoskeleton, Microtubule organizing center, Ruffle
Target Information
CDK6 functions as a cell-cycle initiator protein and is coexpressed and copurified with Cyclin D1. These proteins are critical regulators of cell cycle progression. The prototype member, p34cdc2, and a related protein, cdk2, function late in the cycle, while cdk4 and cdk6 are involved in G1 to S phase progression.
CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in the gene result in microcephaly 12, primary, autosomal recessive (MCPH12).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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