Thermo Fisher Scientific MTOR Monoclonal Antibody (OTI5B1), TrueMAB
Human mTOR 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(Paraffin)에 적합. Lyophilized 형태로 제공되며, PBS buffer와 trehalose 포함. 세포 성장 및 암 연구용으로 최적화된 TrueMAB 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1766–2144 of human MTOR produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
FRAP1 (mTOR) is a serine/threonine kinase essential for cellular growth and proliferation.
Disruption of the mTOR/PI3-kinase/AKT pathway is linked to various cancers.
FRAP1 is the molecular target of rapamycin and its analogs, used as immunosuppressants and cancer therapeutics.
Mutations in this gene are associated with Smith-Kingsmore syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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