Thermo Fisher Scientific STAT6 Polyclonal Antibody
STAT6 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체로, WB, IHC, ELISA, IP 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 친화 크로마토그래피로 정제된 액상 형태, 안정적인 저장 버퍼 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 655–705 of human STAT6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA and 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL-13. STAT6-deficient (Stat6-/-) models show loss of IL-4-mediated functions including Th2 helper T-cell differentiation, surface marker expression, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4-mediated proliferation.
STAT6 mRNA is detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung, and placenta. STAT6 plays a critical role in Th2 immune response and IL-4-mediated biological processes. It naturally exists in two isoforms: STAT6a and STAT6c.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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