Thermo Fisher Scientific Phospho-Doublecortin (Ser297) Polyclonal Antibody
Phospho-Doublecortin (Ser297) 특이적 인식 항체로 인간, 마우스, 랫트 시료에서 WB 검증됨. 세포 내 신경 발달 관련 단백질 DCX의 Ser297 인산화 상태 검출에 적합. 고순도 정제, 액상 형태, -20°C 저장.
- 카탈로그번호
- PA5105768
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-Doublecortin (Ser297) Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DCX (Accession O43602), corresponding to amino acid residues around phosphorylated Ser297 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817167 |
Product Specific Information
This antibody detects endogenous levels of Doublecortin only when phosphorylated at Ser297.
Target Information
In the developing cortex, cortical neurons migrate over long distances to reach their final differentiation site. DCX is a cytoplasmic protein that directs neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains that bind microtubules and interacts with LIS1, a regulatory gamma subunit of platelet activating factor acetylhydrolase. This interaction is crucial for proper microtubule function in the developing cortex. Mutations in the DCX gene cause X-linked lissencephaly.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.