Thermo Fisher Scientific Nogo Polyclonal Antibody
Western blot 및 IHC에 적합한 Nogo 단백항체로, 인간·마우스·랫트 반응성. 합성 펩타이드 면역원 사용. 동결건조 형태로 제공되며 장기 보관 시 -20°C 권장. 연구용으로 ER 형성 및 안정화 관련 단백질 연구에 활용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Goat / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from internal region of human Nogo conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: Nogo.
Target Information
Required to induce the formation and stabilization of endoplasmic reticulum (ER) tubules. They regulate membrane morphogenesis in the ER by promoting tubular ER production. They influence nuclear envelope expansion, nuclear pore complex formation, and proper localization of inner nuclear membrane proteins. Each isoform has specific functions depending on tissue expression. Isoform D is expressed at very low levels in neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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