Thermo Fisher Scientific Synaptophysin Monoclonal Antibody (SYP)
Synaptophysin 단백질을 인식하는 마우스 모노클로날 항체로, 신경세포 시냅스 소포 마커 검출에 사용됩니다. Western blot과 IHC(P)에서 검증되었으며, 인간 시료에 반응합니다. 항원 친화 크로마토그래피로 정제된 액상 항체로, 연구용으로 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SYP |
| Immunogen | A recombinant protein of human Synaptophysin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human pancreas
- Cellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Target Information
Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting an involvement in synaptic vesicle endocytosis. Synaptophysin also plays a role in regulating short-term and long-term synaptic plasticity. It is widely used as a marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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