Thermo Fisher Scientific CAP-18 Polyclonal Antibody
Human CAP-18 단백질을 인식하는 Sheep 유래 Polyclonal 항체. Western blot 및 IHC에 적합. 무보존제 PBS 완충액에 동결건조 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 10–50 µg/mL |
| Immunohistochemistry (IHC) | 10–50 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 70–110 of human CAP-18 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C for short term. For long-term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: Cathelicidin antimicrobial peptide.
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis, and neutrophils.
Cathelicidins are a family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals.
LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. These molecules are essential for defense against invasive bacterial infection in the skin.
Beyond their direct antimicrobial function, Cathelicidins mediate innate and adaptive immunity, including endotoxin neutralization, angiogenesis, wound healing, neutrophil chemotaxis, and mast cell recruitment.
Cathelicidin antimicrobial peptides are considered prototypes for innovative drugs that may treat infection and modulate immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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