Thermo Fisher Scientific BRG1 Polyclonal Antibody
BRG1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 사용 가능. 인간에 반응하며 마우스, 랫, 치킨, 보바인에서 예측 반응성 있음. 항원 친화 크로마토그래피로 정제. 액상 형태로 4°C 또는 -20°C 보관. 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of Human BRG1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.82 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792849 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Rat (100%), Chicken (84%), Bovine (87%)
- Positive Control: 293T, A431, HeLa, HepG2
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair, and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cell differentiation, neurogenesis, cell cycle, etc., and are absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence, and tumor suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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