Thermo Fisher Scientific HDAC8 Monoclonal Antibody (OTI9H8), TrueMAB
HDAC8 단백질을 인식하는 단클론 항체로, Western blot에 적합합니다. Human, Mouse, Rat 반응성이 있으며, IgG1 아이소타입의 Mouse 유래 항체입니다. 동결건조 형태로 제공되며, PBS 버퍼에 8% 트레할로스가 포함되어 있습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- CF809690
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HDAC8 Monoclonal Antibody (OTI9H8), TrueMAB
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9H8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–243 of human HDAC8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
In intact cells, DNA associates with histones and other nuclear proteins to form chromatin. Chromatin remodeling, regulated by acetylation and deacetylation of histones, plays a key role in transcriptional regulation.
Histone acetylation increases accessibility of DNA to transcription factors, while deacetylation is linked to transcriptional silencing.
Mammalian HDAC8, isolated from human kidney, is a nuclear histone deacetylase with homology to other HDACs but distinct tissue distribution. It is involved in tissue development and cancer etiology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.