Thermo Fisher Scientific Phospho-IP3 Receptor 1 (Ser1764) Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Phospho-IP3 Receptor 1 (Ser1764) 폴리클로날 항체로, WB, IHC, ELISA에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다. 세포 내 칼슘 방출 및 세포사멸 관련 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:100–1:300 |
| ELISA | 1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human IP3R-I around the phosphorylation site of S1764 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609014 |
Product Specific Information
This antibody is predicted to react with human and mouse based on sequence homology.
Target Information
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate.
Involved in the regulation of epithelial secretion of electrolytes and fluid through interaction with AHCYL1.
Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis via activation of CaM kinase II, leading to downstream apoptosis pathways.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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