
Thermo Fisher Scientific Phospho-S1P1 (Thr236) Polyclonal Antibody
Phospho-S1P1 (Thr236) 폴리클로날 항체로 인간, 생쥐, 랫드에 반응. Western blot, ICC/IF, ELISA에 사용 가능. 항원 친화 크로마토그래피로 정제된 1 mg/mL 액상 형태. 세포 이동 및 신호전달 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human EDG-1 around the phosphorylation site of T236 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.5% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609210 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
S1P1 is a G-protein coupled receptor for sphingosine 1-phosphate (S1P) that interacts with G(i) proteins. S1P1 signaling activates RAC1, SRC, PTK2/FAK1, and MAP kinases, playing a key role in cell migration through actin cytoskeleton reorganization and lamellipodia formation. It is essential for normal chemotaxis toward S1P and for proper embryonic heart development and cardiac morphogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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