Thermo Fisher Scientific CD13 Polyclonal Antibody
Rabbit 폴리클로날 CD13 항체로 인체 반응성. Western blot에 적합하며, ANPEP 단백질의 중앙 영역(aa 615–641)에서 유래한 합성 펩타이드로 면역화. 액상 형태, PBS 버퍼 및 sodium azide 함유. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 615–641 amino acids from the central region of human ANPEP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2056603 |
Target Information
CD13 (ANPEP) is a 150–170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. It is a metalloprotease that preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides.
CD13 also plays roles in extracellular matrix degradation, antigen processing, and signal transduction. It is important in inflammatory responses, regulates intercellular contact, cell motility, and vascularization.
CD13 is expressed by granulocytes, monocytes, and myeloid leukemia cells, and is involved in protection of leukemic cells against apoptosis. Its expression is associated with poor prognosis of carcinomas.
CD13 functions as an aminopeptidase enzyme and serves as an alpha receptor for coronavirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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