Thermo Fisher Scientific PTPN7 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PTPN7 protein. Validated for Western blot and immunohistochemistry. Supplied in liquid form with 0.5 mg/mL concentration. Suitable for research use in cell signaling and T-cell receptor studies.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 22–51 amino acids from human PTPN7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10977803 |
Target Information
The protein encoded by the PTPN7 gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate cellular processes such as growth, differentiation, mitotic cycle, and oncogenic transformation.
This gene is preferentially expressed in hematopoietic cells and acts as an early response gene in lymphokine-stimulated cells.
The noncatalytic N-terminus of this PTP interacts with MAP kinases to suppress their activity. PTPN7 is involved in T cell antigen receptor signaling through dephosphorylation of molecules in the MAP kinase pathway.
Two alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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