Thermo Fisher Scientific Phospho-beta-2 Adrenergic Receptor (Thr68) Polyclonal Antibody
Phospho-beta-2 Adrenergic Receptor (Thr68)에 특이적으로 결합하는 Rabbit Polyclonal Antibody. Western blot과 IHC(P)에서 검증됨. 액상 형태, 1 mg/mL 농도. 내인성 ADRB2의 Thr68 인산화 상태만 검출. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ADRB2 (Accession P07550), corresponding to amino acid residues around phosphorylated Thr68 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816903 |
Product Specific Information
Antibody detects endogenous levels of ADRB2 only when phosphorylated at Thr68.
Target Information
Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine. Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family.
Nine receptor subtypes have been identified thus far including:
- Three alpha-1 AR subtypes (1A/D, 1B, and 1C)
- Three alpha-2 ARs (2A, 2B, and 2C)
- Three beta AR subtypes (1, 2, and 3)
ARs participate in either the onset or maintenance of several disease states including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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