Thermo Fisher Scientific Phospho-HSP90 alpha (Tyr197) Polyclonal Antibody
인산화된 Tyr197 위치의 HSP90α를 특이적으로 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(파라핀) 분석에 적합. 인간, 생쥐, 랫트 반응성. 고순도 정제, 1 mg/mL 농도, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HSP90AA1 (Accession P07900), corresponding to amino acid residues around phosphorylated Tyr197 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816905 |
Product Specific Information
This antibody detects endogenous levels of HSP90 alpha only when phosphorylated at Tyr197.
Target Information
Heat shock proteins (HSPs) are expressed in response to various biological stresses, including heat.
HSP90 is a 90 kDa protein that is highly expressed under both stress and non-stress conditions.
It interacts with multiple intracellular proteins such as steroid receptors, actin, tubulin, and kinases.
HSP90 is essential for maintaining the structural integrity of steroid receptors, enabling ligand binding during receptor activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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