Thermo Fisher Scientific Phospho-Lyn (Tyr193) Polyclonal Antibody
Lyn 단백질의 Tyr193 인산화 형태를 특이적으로 검출하는 rabbit polyclonal antibody. Western blot 및 IHC(파라핀)에서 사용 가능. Human, Mouse, Rat 반응성. 액상 형태로 -20°C 보관. 연구용 전용 제품.
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- PA5105478
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LYN (Accession P07948), corresponding to amino acid residues around phosphorylated Tyr193. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816906 |
Product Specific Information
Antibody detects endogenous levels of Lyn only when phosphorylated at Tyr193.
Target Information
Lyn proto-oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well-studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells, with exclusion in T lymphocytes. It has also been observed that Lyn plays diverse roles such as in regulation of B cell receptor signaling, mast cell signaling, and Epithelial-Mesenchymal Transition (EMT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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