Thermo Fisher Scientific ACVRL1 Polyclonal Antibody
인간 Activin Receptor-Like Kinase 1을 검출하는 Goat Polyclonal Antibody. Western blot 및 ELISA에 적합하며, 비결합형 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 시약.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.2 µg/mL |
| ELISA | 0.5–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment of human Activin Receptor-Like Kinase 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2257882 |
Product Specific Information
PA1-20176 detects Activin Receptor-Like Kinase 1 in human samples.
Target Information
Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands.
ACVRL1, similar to other type 1 receptors, has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail.
Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2.
Mutations in ACVRL1 have also been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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