Thermo Fisher Scientific C/EBP alpha Recombinant Rabbit Monoclonal Antibody (SD202-09)
C/EBP alpha 단백질을 표적하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot에 최적화되어 있으며 높은 특이성과 재현성을 제공. HEK293 세포에서 발현된 IgG 형식으로, Protein A로 정제된 액상 형태. 인간, 생쥐, 랫드 반응성.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SD202-09 |
| Immunogen | Synthetic peptide within C-terminal Human CEBP alpha (aa 309–358) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809652 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
The C/EBP (CCAAT/enhancer binding protein) family of transcription factors—alpha, beta, delta, and epsilon—are widely expressed proteins found in various tissues. These domains contain an evolutionarily conserved five-amino acid motif (RDM) conforming to the consensus sequence (I/V/L)KXEP.
C/EBP proteins play key roles in metabolic regulation in liver and adipose cells and act in cascades aiding adipocyte development. C/EBP beta isoforms (LAP*, LAP, and LIP) differ in translation initiation and gene regulation functions.
In neurological contexts, C/EBPs are involved in nerve growth factor mediation, synaptic plasticity, and inflammatory responses in Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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