Thermo Fisher Scientific HERV-FRD Polyclonal Antibody
HERV-FRD 단백질을 인식하는 Thermo Fisher Scientific의 고순도 폴리클로날 항체입니다. Western blot에 최적화되어 있으며 인간, 생쥐, 랫트에 반응합니다. 항원 친화 크로마토그래피로 정제되었고 PBS/glycerol 버퍼에 보존됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific HERV-FRD Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution
- 1:1,000–1:4,000
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human HERV-FRD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.2) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2719856 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. The purity is >95% as confirmed by SDS-PAGE.
Target Information
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have retained, lost, or modified their original functions during evolution.
This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can form pseudotypes with MLV, HIV-1, or SIV-1 virions and confer infectivity.
Human endogenous retroviruses (HERVs) constitute approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]). [Supplied by OMIM]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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