Thermo Fisher Scientific DMRT1 Monoclonal Antibody (OTI5D6), TrueMAB
인간 DMRT1 단백질(1-210 aa)에 특이적인 Mouse IgG1 단일클론 항체. Western blot에 적합하며, carrier-free 형태로 재결합 및 결합 실험에 활용 가능. PBS, trehalose buffer로 안정화되어 -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–210 of human DMRT1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended desalting product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The DMRT1 gene belongs to a cluster with two other family members sharing a zinc finger-like DNA-binding motif (DM domain).
This domain is a conserved component of vertebrate sex-determination pathways and regulates male development in various species.
DMRT1 shows gonad-specific, sexually dimorphic expression.
Defective testicular development and XY feminization occur when this gene is hemizygous.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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