Thermo Fisher Scientific DMRT1 Monoclonal Antibody (OTI2A10), TrueMAB
DMRT1 단백질을 인식하는 마우스 단일클론 항체로, Western blot에 최적화되어 있습니다. Human 시료에 반응하며, 동결건조 형태로 제공됩니다. PBS 버퍼에 8% 트레할로스 포함, 보존제 무첨가. -20°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–210 of human DMRT1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The DMRT1 gene belongs to a cluster with other family members sharing a zinc finger-like DNA-binding motif (DM domain).
This conserved DM domain plays a crucial role in vertebrate sex determination and male development.
The gene shows gonad-specific, sexually dimorphic expression, and defects can lead to abnormal testicular development and XY feminization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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