Thermo Fisher Scientific MEK1/MEK2 Monoclonal Antibody (E.901.7)
MEK1/MEK2 단백질을 특이적으로 인식하는 토끼 단클론 항체. Western blot에 최적화되어 있으며, 인간, 마우스, 랫 등 다양한 종에 반응. 액상 형태로 제공되며, -20°C에서 보관. 세포 성장과 분화 조절 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Non-human primate, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E.901.7 |
| Immunogen | Synthetic peptide corresponding to the sequence of human MEK1/2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 45 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10980233 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
MEK1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003).
In the brain, this pathway also plays a key role in synaptic signaling (Adams and Sweatt, 2002).
Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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