Thermo Fisher Scientific P2X7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 47-334 of human P2RX7 (NP_0025533) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:P2X7,uniProtId:Q99572-1,ncbiNodeId:9606,antigenRange:47-334,antigenLength:595,antigenImageFileName:PA5-87959_P2X7_Q99572-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87959_P2X7_Q99572-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.21 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804541

Product Specific Information

Positive Samples: A375, HT-29, U-251MG, LO2, Mouse heart, Rat liver; Cellular Location: Cell membrane, Multi-pass membrane protein

Immunogen sequence: SDKLYQRKEP VISSVHTKVK GIAEVKEEIV ENGVKKLVHS VFDTADYTFP LQGNSFFVMT NFLKTEGQEQ RLCPEYPTRR TLCSSDRGCK KGWMDPQSKG IQTGRCVVYE GNQKTCEVSA WCPIEAVEEA PRPALLNSAE NFTVLIKNNI DFPGHNYTTR NILPGLNITC TFHKTQNPQC PIFRLGDIFR ETGDNFSDVA IQGGIMGIEI YWDCNLDRWF HHCRPKYSFR RLDDKTTNVS LYPGYNFRYA KYYKENNVEK RTLIKVFGIR FDILVFGTGG KFDIIQLV

Target Information

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay criteria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.