Thermo Fisher Scientific NKCC2 Polyclonal Antibody
Thermo Fisher Scientific의 NKCC2 Polyclonal Antibody는 Mouse 및 Rat 시료에서 반응하며, Western blot과 ELISA에 적합합니다. 인간 SLC12A1의 합성 펩타이드로부터 제작된 Rabbit IgG 폴리클로날 항체로, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 50–150 of human SLC12A1 (NP_0003292) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.71 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805209 |
Product Specific Information
- Immunogen sequence: FGDEAQKRLR ISFRPGNQEC YDNFLQSGET AKTDASFHAY DSHTNTYYLQ TFGHNTMDAV PKIEYYRNTG SISGPKVNRP SLLEIHEQLA KNVAVTPSSA D
- Positive Samples: Mouse Kidney, Rat Kidney
- Cellular Location: Membrane, Multi-pass membrane protein
Target Information
The sodium-potassium-chloride cotransporter isoform 2 (NKCC2) is kidney-specific and located on the apical membrane of the thick ascending limb of Henle’s loop and the macula densa. It mediates NaCl resorption with a stoichiometry of 1Na:1K:2Cl and is sensitive to diuretics such as furosemide and bumetanide. Defects in this gene are associated with Bartter-like syndromes.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-88905_NKCC2_Q13621-1_Rabbit.svg, PA5-88905_NKCC2_Q13621-1_Rabbit_PDP.jpeg)
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